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Flexible HPLC instrument setups for double usage as one heart-cut-2D-LC system or two independent 1D-LC systems
Description
The Technical Note describes how to setup single heart-cut 2D-LC instruments with the Vanquish platform, applying solvent strength reduction and trapping of the cut fraction. In addition instruments are described, which can be flexibly utilized either as one heart-cut 2D-LC instrument or as two 1D-LC instruments.Market: | Pharma |
Keywords: | Chromeleon, 2D-HPLC, 2D-LC, two-dimensional liquid chromatography, Vanquish Dual Split Sampler, heart-cut-2D-LC, SII for Empower, SII for Xcalibur, Vanquish Duo UHPLC System |
Author: | Maria Grübner, Giorgia Greco |
Affiliation: | Thermo Fisher Scientific, Germering, Germany |
Status: | Proof of Concept |