Clinical research method for the quantitative determination of free plasma serotonin and 5-hydroxyindoleacetic acid (5-HIAA) in human plasma by UHPLC-MS/MS
Descriptionclinical research method for the quantitation of serotonin and 5-HIAA from human plasma for clinical research. Thermo Scientific™ SOLA™ SAX solid phase extraction (SPE) technology is used for sample clean-up of the plasma prior to analysis.A Thermo Scientific™ Acclaim™ Vanquish PA2 UHPLC 2.2 µm column is used on the Thermo Scientific™ Vanquish Horizon™ UHPLC system coupled with the Thermo Scientific™ TSQ Quantiva™ MS/MS.
|Keywords:||SOLA SAX, Solid phase extraction, Serotonin, Vanquish, plasma, MS/MS, UHPLC, Reversed phase, polar advantage ii, bioanalysis, triple quad, Acclaim Vanquish, quantiva, SSRIs|
|Author:||Callum Taylor and Kean Woodmansey|
|Affiliation:||Thermo Fisher Scientific|
For Research Use Only. Not for use in diagnostic procedures.