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Clinical research method for the quantitative determination of free plasma serotonin and 5-hydroxyindoleacetic acid (5-HIAA) in human plasma by UHPLC-MS/MS Be the first to rate this application


clinical research method for the quantitation of serotonin and 5-HIAA from human plasma for clinical research. Thermo Scientific™ SOLA™ SAX solid phase extraction (SPE) technology is used for sample clean-up of the plasma prior to analysis.A Thermo Scientific™ Acclaim™ Vanquish PA2 UHPLC 2.2 µm column is used on the Thermo Scientific™ Vanquish Horizon™ UHPLC system coupled with the Thermo Scientific™ TSQ Quantiva™ MS/MS.
Market: Clinical Research
Keywords: SOLA SAX, Solid phase extraction, Serotonin, Vanquish, plasma, MS/MS, UHPLC, Reversed phase, polar advantage ii, bioanalysis, triple quad, Acclaim Vanquish, quantiva, SSRIs
Matrix: Human plasma
Author: Callum Taylor and Kean Woodmansey
Affiliation: Thermo Fisher Scientific
Uploaded on 10/24/2019.

For Research Use Only. Not for use in diagnostic procedures.