Accurate and reliable quantitation of p-toluenesulfonates genotoxic impurities in an active pharmaceutical ingredient by HPLC-UV
DescriptionIn this work, an HPLC-UV method for the quantitation of four p-toluenesulfonates is presented. The determination of linearity, limit of detection (LOD), limit of quantification (LOQ), and recovery rates are shown.
|Keywords:||UV detection, Active pharmaceutical ingredient, aprepitant, Genotoxic impurities, p-toluenesulfonates|
|Author:||Sylvia Grosse, Mauro De Pra, Frank Steiner|
|Affiliation:||Thermo Fisher Scientific, Germering, Germany|
For Research Use Only. Not for use in diagnostic procedures.