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Accurate and reliable quantitation of p-toluenesulfonates genotoxic impurities in an active pharmaceutical ingredient by HPLC-UV Be the first to rate this application


In this work, an HPLC-UV method for the quantitation of four p-toluenesulfonates is presented. The determination of linearity, limit of detection (LOD), limit of quantification (LOQ), and recovery rates are shown.
Market: Pharma
Keywords: UV detection, Active pharmaceutical ingredient, aprepitant, Genotoxic impurities, p-toluenesulfonates
Matrix: Acetontrile, Water
Author: Sylvia Grosse, Mauro De Pra, Frank Steiner
Affiliation: Thermo Fisher Scientific, Germering, Germany
Uploaded on 8/30/2019.

For Research Use Only. Not for use in diagnostic procedures.