Thermo Scientific AppsLab Library: HPLC charged aerosol detector analysis of polysorbate 80 and insulin in a biopharmaceutical formulation

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Description

This application shows a method for HPLC-CAD analysis of polysorbate 80 and insulin in a biopharmaceutical formulation. The characterization and quantification of polysorbates is difficult because these compounds are heterogeneous mixtures with no chromophore. Because polysorbates are used in final formulations, determination of lot-to-lot variability is critical to both the pharmaceutical and biopharmaceutical industries.

Market:	BioPharma
Keywords:	Charged aerosol detector, Polysorbate, Tween, CAD, Biopharmaceuticals
Matrix:	biopharmaceutical formulation
Author:	Thermo Fisher Scientific
Affiliation:	Thermo Fisher Scientific

Uploaded on 8/9/2019.

For Research Use Only. Not for use in diagnostic procedures.