HPLC charged aerosol detector analysis of polysorbate 80 and insulin in a biopharmaceutical formulation
DescriptionThis application shows a method for HPLC-CAD analysis of polysorbate 80 and insulin in a biopharmaceutical formulation. The characterization and quantification of polysorbates is difficult because these compounds are heterogeneous mixtures with no chromophore. Because polysorbates are used in final formulations, determination of lot-to-lot variability is critical to both the pharmaceutical and biopharmaceutical industries.
|Keywords:||Charged aerosol detector, Polysorbate, Tween, CAD, Biopharmaceuticals|
|Author:||Thermo Fisher Scientific|
|Affiliation:||Thermo Fisher Scientific|
For Research Use Only. Not for use in diagnostic procedures.