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AN73053: Assay of Potassium Bitartrate using Ion Chromatography
Description
We developed an ion chromatography (IC) method to replace the titrimetric assay for potassium bitartrate in the United States Pharmacopeia (USP) Potassium Bitartrate monograph. Our IC method offers a significant improvement to the existing assay in the USP monograph. It is a 5 min method that uses a Dionex™ IonPac™ AS20 ion-exchange column, an electrolytically generated KOH eluent, and suppressed conductivity detection on a Thermo Scientific™ Dionex™ Reagent-Free™ Ion Chromatography (RFIC™) system supported by regulatory compliant Chromeleon™ Chromatography Data System (CDS) software.| Market: | Pharma |
| Keywords: | Dionex IonPac AS20 Column, Drug Substance, Pharmaceutical, USP monograph, suppressed conductivity detection, Tartrate, RFIC System, AN 73053 |
| Matrix: | DI water |
| Author: | Beibei Huang and Jeffrey Rohrer |
| Affiliation: | Thermo Fisher Scientific, Sunnyvale, CA USA |
For Research Use Only. Not for use in diagnostic procedures.
