Thermo Scientific AppsLab Library: Identity confirmation and accurate quantitation of a genotoxic impurity in an active pharmaceutical ingredient by UHPLC-UV coupled to a single quadrupole mass detector

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Identity confirmation and accurate quantitation of a genotoxic impurity in an active pharmaceutical ingredient by UHPLC-UV coupled to a single quadrupole mass detector Be the first to rate this application

Description

Confirm the identity of related impurities and a genotoxic impurity in a drug substance by single quadrupole mass detector. Accurately quantify the genotoxic impurity by UV detection.

Market:	Pharma
Keywords:	UV detection, ISQ EM, aprepitant, Genotoxic impurities, mass detection, methyl-p-toluenesulfonate, single quadrupole, Autospray
Matrix:	Acetonitrile, Water
Author:	Sylvia Grosse, Mauro De Pra, Frank Steiner
Affiliation:	Thermo Fisher Scientific, Germering, Germany

Uploaded on 6/12/2019.

For Research Use Only. Not for use in diagnostic procedures.