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AN72907: Determination of Fluoride in Tooth Gel Containing Sodium Fluoride Be the first to rate this application


Here we demonstrate that a Dionex IonPac AS15-5μm column can be used to analyze tooth gel samples for the content of fluoride. Fluoride is separated from other anions using KOH eluent generated electrolytically with a EGC III KOH cartridge and detected by suppressed conductivity. Method performance is evaluated according to the system suitability requirements described in the proposed United States Pharmacopeia (USP) monograph revision for the assay and the acceptance criterion set for sodium fluoride content in a tooth gel sample.
Market: Pharma
Keywords: Toothpaste, ICS-6000, IonPac AS15-5μm column, OTC, USP Pharmacopeia Forum (PF) 44(4), USP Sodium Fluoride Gel monograph, USP<621>
Matrix: Tooth gel sample solution
Author: Manali Aggrawal and Jeff Rohrer
Affiliation: Thermo Fisher Scientific
Uploaded on 1/7/2019.