AN72907: Determination of Fluoride in Tooth Gel Containing Sodium Fluoride
DescriptionHere we demonstrate that a Dionex IonPac AS15-5μm column can be used to analyze tooth gel samples for the content of fluoride. Fluoride is separated from other anions using KOH eluent generated electrolytically with a EGC III KOH cartridge and detected by suppressed conductivity. Method performance is evaluated according to the system suitability requirements described in the proposed United States Pharmacopeia (USP) monograph revision for the assay and the acceptance criterion set for sodium fluoride content in a tooth gel sample.
|Keywords:||Toothpaste, ICS-6000, IonPac AS15-5μm column, OTC, USP Pharmacopeia Forum (PF) 44(4), USP Sodium Fluoride Gel monograph, USP<621>|
|Matrix:||Tooth gel sample solution|
|Author:||Manali Aggrawal and Jeff Rohrer|
|Affiliation:||Thermo Fisher Scientific|