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Profiling of Sialylated Oligosaccharides in Mammalian Milk Using Online Solid Phase Extraction-Hydrophilic Interaction Chromatography Coupled with Negative-Ion Electrospray MS Be the first to rate this application

profiling sialylated oligosaccharides mammalian milk using online solid phase extractionhydrophilic interaction chromatography coupled with negativeion electrospray ms


Sialylated oligosaccharides are important components in mammalian milk. They play a key role in the health and growth of infants by helping to shape up infant’s gastrointestinal microbiota and defense against infection by various pathogenic agents. A detailed knowledge of the structures, compositions, and quantities of the sialylated milk oligosaccharides (SMOs) is a prerequisite for understanding their biological roles. However, because of the presence of very large amounts of lactose and neutral oligosaccharides, accurate analysis of SMOs is difficult. An online SPE-HILIC-MS was developped.
Market: Food and Beverage
Matrix: Acetonitrile, Water
Uploaded on 12/17/2018.

For Research Use Only. Not for use in diagnostic procedures.