Application of HPLC-UV-CAD in the consistency evaluation of cefepime injections
DescriptionHPLC-UV-CAD method was established in this paper and the consistency of the generic drug for cefepime of injection was evaluated from the impurity profile and excipients. On the basis of UV detection and the charged aerosol detection (CAD) combined with a mixed matrix column Trinity-P1. By adjusting the organic phase and salt concentration, a method for determining the arginine of the auxiliary material was established. The determination can be made simultaneously with the main component of the drug and the salt forming ion.
For Research Use Only. Not for use in diagnostic procedures.