AN72792: Determination of Etimicin and Related Impurities in Etimicin Sulfate
DescriptionThis application note demonstrated that the ChP Etimicin Sulfate monograph etimicin assay method and the method for organic impurities could be successfully executed with a Dionex IonPac AmG-3µm C18 column on an ICS-5000+ system. The separation, linearity, reproducibility, and sensitivity were found to meet or exceed the current ChP Etimicin Sulfate monograph performance requirements. This method is reliable and can be used for the routine monitoring of etimicin.
|Keywords:||aminoglycoside, Antibiotic, Drug Substance, Electrochemical detection, PAD, Dionex ICS 5000+ HPIC system, Dionex ICS-6000, Dionex IonPac AmG-3µm C18 column, China Pharmacopeia, ion-pair reversed-phase HPLC, ChP|
|Author:||Jingli Hu and Jeffrey Rohrer|
|Affiliation:||Thermo Fisher Scientific|
For Research Use Only. Not for use in diagnostic procedures.