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Oligonucleotide characterization for quality control and increased productivity by single quadrupole mass spectrometer with extended mass range Be the first to rate this application

dna quality control by lcms


We demonstrate increased productivity in the analysis of synthetic oligonucleotides between 29 and 40 base pairs in length by incorporating the Thermo Scientific ISQ EM single quadrupole mass spectrometer into a UV-based quality control method
Market: Pharma
Keywords: UHPLC, LC-MS, Vanquish Flex UHPLC, Single quadrupole mass spectrometer, ISQ EM, extended mass range, high-performance liquid chromatography, oligonucleotides, quality control, ssDNA
Matrix: Water
Author: Katherine Lovejoy, Sylvia Grosse, Mauro de Pra, Martin Samonig, Frank Steiner
Affiliation: Thermo Fisher Scientific, Germering, Germany
Uploaded on 9/14/2018.

For Research Use Only. Not for use in diagnostic procedures.