Oligonucleotide characterization for quality control and increased productivity by single quadrupole mass spectrometer with extended mass range
DescriptionWe demonstrate increased productivity in the analysis of synthetic oligonucleotides between 29 and 40 base pairs in length by incorporating the Thermo Scientific ISQ EM single quadrupole mass spectrometer into a UV-based quality control method
|Keywords:||UHPLC, LC-MS, Vanquish Flex UHPLC, Single quadrupole mass spectrometer, ISQ EM, extended mass range, high-performance liquid chromatography, oligonucleotides, quality control, ssDNA|
|Author:||Katherine Lovejoy, Sylvia Grosse, Mauro de Pra, Martin Samonig, Frank Steiner|
|Affiliation:||Thermo Fisher Scientific, Germering, Germany|
For Research Use Only. Not for use in diagnostic procedures.