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Accurate and precise quantification of mAb-released N-glycans with an amide HILIC column
Description
This application note demonstrated the robustness, reproducibility, accuracy, and precision of quantification of IgG N-glycans using the Thermo Scientific™ Vanquish™ Horizon UHPLC integrated biocompatible system and Thermo Scientific™ Accucore™ 150 Amide HILIC column.Market: | BioPharma |
Keywords: | Column lifetime, Solid core, Vanquish UHPLC, IgG, Quantification, 2-AB label, Accucore 150 Amide HILIC column, APTS label, Inter- and intra-column reproducibility, NIST mAb, released N-glycan |
Matrix: | Water |
Author: | Xin Zhang, Xuefei Sun |
Affiliation: | Thermo Fisher Scientific |