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HPLC-CAD impurity profiling of carbocisteine using SCX-RP mixed-mode chromatography
Description
The goal of this application is to analyze the non-proteinogenic amino acid carbocisteine and its impurities using HPLC-CAD (Charged Aerosol Detection) and to obtain improved sensitivity for the impurities when compared to the existing method.Market: | Pharma; Chemical |
Keywords: | Amino acids, Carbocisteine, Vanquish CAD, impurity profiling, LOQ, mixed-mode chromatography |
Matrix: | Water |
Author: | Klaus Schilling, Ruben Pawellek, Oliver Wahl, Ulrike Holzgrabe |
Affiliation: | University of Wuerzburg, Germany |