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Fast methods for the determination of ibuprofen in drug products

Description
This application note demonstrates straightforward approaches to improve the throughput compared with the USP 40 method by using a 50 × 2.1 mm column, with a 2.6 μm particle size, operated in a UHPLC instrument (Thermo Scientific™ Vanquish™ Horizon UHPLC system), while maintaining USP acceptance criteria on relative retention time, resolution, and tailing factors. The UHPLC system was run with Empower 3Market: | Pharma |
Keywords: | Ibuprofen, Pharmaceutical, Valerophenone, Chromeleon CDS, Drug, DII for Empower software, USP 40 monograph, Empower 3 |
Matrix: | Tablet |
Author: | Sylvia Grosse, Mauro De Pra, Frank Steiner |
Affiliation: | Thermo Fisher Scientific, Germering, Germany |
For Research Use Only. Not for use in diagnostic procedures.