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AU72648: Determination of Gentamicin and Related Impurities in Gentamicin Sulfate using Simple Eluents (Part A)
Description
This application update demonstrates that gentamicin sulfate and related impurities can be separated with a Dionex IonPac AmG-3µm C18 column using a simple eluent method (100 mM TFA (trifluoroacetic acid) and no organic solvent. (Method A in AU 72648)). This method meets or exceeds the performance criteria for Content of Gentamicins in the United States Pharmacopeia (USP) Gentamicin Sulfate monograph.Market: | Pharma |
Keywords: | aminoglycoside, Antibiotic, Drug Substance, Electrochemical detection, USP, PAD, Dionex ICS 5000+ HPIC system, Dionex ICS-6000, Dionex IonPac AmG-3µm C18 column, EP, ion pair reversed phase HPLC |
Matrix: | Water |
Author: | Jingli Hu and Jeffrey Rohrer |
Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.