Thermo Scientific AppsLab Library: Quantification of paclitaxel, its degradants and related substances using UHPLC with charged aerosol detection

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Description

This application shows the quantification of multiple impurities with a single calibrant by taking advantage of the uniform response of the charged aerosol detector (CAD). The inverse gradient compensation wizard is also highlighted.

Market:	Pharma
Keywords:	Paclitaxel, Taxane, Charged aerosol detection, Impurity analysis, Vanquish Flex Duo UHPLC, forced degradation, global calibration, inverse gradient, stability analysis, Taxol
Matrix:	Methanol
Author:	Menz, Michael(1); Steiner, Frank(1); Acworth, Ian(2)
Affiliation:	(1) Thermo Fisher Scientific, Germering, Germany; (2) Thermo Fisher Scientific, Chelmsford, MA, USA

Uploaded on 2/22/2018.