Thermo Scientific AppsLab Library: The determination of elemental impurities in vitamin B12 supplements using the Thermo Scientific iCAP TQ ICP-MS

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The determination of elemental impurities in vitamin B12 supplements using the Thermo Scientific iCAP TQ ICP-MS Be the first to rate this application

Chemical structure of Vitamin B12.

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Description

To demonstrate the accurate determination of elemental impurities, especially As, in vitamin B12 according to the method outlined in USP chapter <233>, Elemental Impurities - Procedures. To demonstrate that triple quadrupole (TQ) ICP-MS can be easy to use and methods can be set up through a dedicated tool, Reaction Finder, which automatically selects optimized parameters with respect to reaction gas and product ion mass.

Market:	Pharma; Food and Beverage
Keywords:	arsenic, interference removal, oxygen, reaction gases, triple quadrupole, USP 232, USP 233, USP 2232
Matrix:	aqueous, vitamin B12 supplement
Author:	Daniel Kutscher, Marcus Manecki, Shona McSheehy Ducos,
Affiliation:	Thermo Fisher Scientific Bremen, Germany

Uploaded on 9/8/2017.

For Research Use Only. Not for use in diagnostic procedures.