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A comparison between HRAM Orbitrap technology and MS/MS for the analysis of polyfluoroalkyl substances by EPA Method 537
Description
We present a liquid chromatography – high-resolution, accurate-mass (LC-HRAM) methodology using Orbitrap technology as a sensitive, accurate, and reliable quantitative alternative to the use of triple quadrupole mass spectrometers while simultaneously determining unknown perfluorinated compounds in the same drinking water extracts. Based on the EPA method flexibility rule, QA/QC requirements and guidance within EPA Method 537, HRAM Orbitrap technology should be permissible for potential compliance monitoring if PFASs become regulated compounds in US drinking waters.| Market: | Water Analysis |
| Keywords: | PFOA, PFOS, CEC, contaminants of emerging concern, Orbitrap, POPs, Persistent Organic Pollutants, fire-fighting foam, perfluorinated alkyl substances, perfluorinated compound, perfluoroalkyl acid, perfluoroalkyl acids, PFAA, PFAS |
| Matrix: | Water |
| Author: | Ali Haghani, Andy Eaton, Richard F. Jack, Ed George, Dipankar Ghosh |
| Affiliation: | Eurofins Eaton Analytical, Inc. and Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.
