Thermo Scientific AppsLab Library: Enabling online monitoring of mAb titer and product quality in bioreactors with an aseptic autosampler-ready HPLC configuration as PAT tool

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Enabling online monitoring of mAb titer and product quality in bioreactors with an aseptic autosampler-ready HPLC configuration as PAT tool Be the first to rate this application

Description

The integration of Thermo Scientific Vanquish HPLC and UHPLC Systems with an aseptic autosampler enables automated online sample delivery and analysis for pseudo real-time monitoring of protein titer and critical quality attributes (CQAs) during upstream process development.

Market:	BioPharma
Keywords:	SEC, mAb, Protein A, SCX, Charge Variants, 2D-LC, PAT, size variants, process analytical technologies, CQA
Matrix:	Cell culture

Uploaded on 9/2/2026.

For Research Use Only. Not for use in diagnostic procedures.