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AN246: Determination of Ethylene Glycol in a Sorbitol Solution Be the first to rate this application

determination ethylene glycol

Description

Glycerin, sorbitol, and propylene glycol (PG) are widely used in pharmaceuticals and personal care products. These products are at risk from adulteration by similar, less costly, and very toxic compounds (ethylene glycol (EG) and diethylene glycol (DG)). The United States Pharmacopeia (USP) as directed by the US FDA revised USP 32 NF 26–27 monographs to identify and quantify EG and DEG in PG, sorbitol, and glycerin solutions. Here EG in sorbitol solution is separated by HPAE on CarboPac MA1 column, optimized for the separation of sugar alcohols and detected by PAD with Au working electrode.
Market: Food and Beverage
Keywords: Electrochemical detection, Ethylene glycol, Sugar alcohols, NaOH, CarboPac MA1 column, Sorbitol solution, alternative USP 32 NF 26–27 monographs, alternative USP Ethylene Glycol monograph, glycerin, Glycerol, Sorbitol, HPAE-PAD, TN71, TN 20, TN 70671, TN20, TN70671, AN 246
Matrix: Sorbitol solution
Author: Terri Christison, Brian De Borba, and Jeff Rohrer
Affiliation: Thermo Fisher Scientific, Sunnyvale, CA USA
Uploaded on 2/28/2015.

For Research Use Only. Not for use in diagnostic procedures.